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DTSTAMP:20260626T031404Z
DTSTART:20220405T170000
DTEND:20220405T180000
SUMMARY:How to Yeast Lipidomics Research | The Lipidomics Webinar | with Christian Klose
DESCRIPTION:Yeast is a powerful model system for cell and molecular biology research. What should be considered when conducting yeast lipidomics?\nThe yeast&nbsp\;Saccharomyces cerevisiae&nbsp\;is a powerful model system for cell and molecular biology research. This is mostly due to the availability of simple and straightforward genetic and molecular tools and methods to manipulate almost any cell biological process.\nLipidomics has become an indispensable method for the quantitative assessment of lipid metabolism and membrane biology in studies employing yeast as an experimental system. Here we show how lipidomics is applied to investigate the influence of a variety of commonly used growth conditions on the yeast lipidome\, including glycerophospholipids\, triglycerides\, ergosterol as well as complex sphingolipids\, establishing a baseline for future lipidomic experiments in yeast.\nBased on this work\, we review acyl chain remodeling as a fundamental aspect of membrane biology\, the roles of lipids in the unfolded protein response (UPR) in both endoplasmic reticulum (ER) and mitochondria\, as well as the lipid-based regulation of key biological process like control of cell size and growth rate. These studies provide mechanistic insights into the amazing diversity of lipid functions in essential cellular processes conserved throughout the eukaryotic domain of life.\nJoin the webinar for free and get in touch with the experts.\nRegistration
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