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UID:6a2d52264ffee@www.leap-up.com
DTSTAMP:20260613T145046Z
DTSTART:20260609T100000
DTEND:20260609T110000
SUMMARY:Webinar: Live Imaging of the Extracellular Matrix With a Glycan-Binding Fluorophore
DESCRIPTION:Visualizing the extracellular matrix (ECM) in real-time has long been a challenge. Dr. Kayvon Pedra’s group has developed a novel\, cell-impermeant fluorophore that red-shifts and activates upon binding glycans. This allows for seamless\, wash-free imaging of glycosylated ECM architecture - from in vitro models to in vivo mouse tumors - providing a powerful new tool for live fluorescence microscopy.\nHighlights of the presentation\n\nA cell-impermeable small molecule fluorophore turns on and red-shifts upon binding glycosylated biomolecules.\nApplication of the dye to live biological samples enables wash-free visualization of extracellular matrix structure.\nObservations demonstrate no toxicity\, a broad substrate profile\, deep tissue penetration\, and negligible photobleaching in a variety of model organisms.\n
LOCATION:Virtual Zoom Meeting
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