Precision oncology offers new hope for lung cancer

A patient with advanced lung cancer and metastases received customised treatment based on genetic testing. The tests revealed an EGFR driver mutation that promotes tumour growth. Targeted tablet therapy initially led to a remission of the cancer - with the exception of one affected lymph node. Instead of switching to standard therapies, the UKL experts focussed on advanced molecular diagnostics.

They discovered a second mutation that was not detected by the previous therapy. By specifically adjusting the medication with a new active ingredient, the cancer could be further reduced.

This case impressively demonstrates how important individual genetic analysis is for successful treatment. Traditional treatment approaches such as chemotherapy or immunotherapy might not have been effective enough in this case. „It is worth looking for new ways and not giving up prematurely“, emphasises Prof. Dr Hubert Wirtz, Head of Pneumology at the UKL.

The approach of precision oncology can significantly increase the chances of survival for many patients - a concrete example of the guiding principle of World Cancer Day that every cancer patient is unique and deserves individualised treatment.

Press release from "Leipzig University Hospital" dated 30 January 2025