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Roche buys biotech company 89bio for up to 3.5 billion dollars

Roche is expanding its pharma portfolio and acquiring the US biotech company 89bio, which specialises in innovative therapies for liver and cardiometabolic diseases. At its heart is the drug candidate pegozafermin, a specially developed FGF21 analogue with an extended half-life and optimised biological activity. It is currently being tested in phase 3 trials in patients with advanced MASH and severe hypertriglyceridaemia.
18/09/2025

With pegozafermin, 89bio could open up a new generation of treatment options where few effective therapies are currently available. The candidate is considered particularly promising for patients with moderate to severe MASH, as it has the potential to fundamentally change the standard of care.

For Roche, the integration of 89bio offers the opportunity to further expand its position in cardiovascular, renal and metabolic diseases and to leverage its own development and manufacturing network for accelerated market access. The acquisition is expected to be completed in 2025, until then 89bio will continue to operate independently.

Press release from "89bio, Inc. "dated 18 September 2025

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