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New hope for Alzheimer's sufferers from Leipzig

A patient has been treated with the new antibody lecanemab for the first time at Leipzig University Hospital. For the 66-year-old woman, this marks the start of a therapy that can noticeably slow down the progression of Alzheimer's disease in its early stages. Experts regard the active substance as an important breakthrough, as no treatment to date has been able to reliably slow down the progression of the disease.
11/11/2025

A large team led by Prof. Dr Dorothee Saur has spent months setting up the complex processes and organising interdisciplinary collaboration between the neurology, neuroradiology and nuclear medicine departments. The patient now receives an infusion every fortnight and is closely monitored with MRI and PET in order to precisely track the effect and possible reactions in the brain. The aim is to visibly reduce pathological amyloid deposits and maintain the patient's ability to carry out everyday activities for as long as possible. The therapy is still only suitable for a small group, but interest is huge. Around fifty people a week contact the dementia consultation centre to have their chances assessed. With donanemab, a second active substance is already available that is also suitable for early stages. Experts are expecting further progress and are hoping for a turning point for many sufferers and their families.

Press release from "Universitätsklinikum Leipzig" dated 11 November 2025

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