Functionality of adrenaline-binding receptors decoded
G protein-coupled receptors (GPCRs) are central to many biological processes, but the signalling process was previously unclear. The team led by Prof. Dr Peter W. Hildebrand used computer-aided molecular dynamics simulations and biochemical analyses to show how the β2 adrenergic receptor transmits signals within the cell. These findings are particularly relevant for the development of drugs with fewer side effects. The study was published in "Nature Structural & Molecular Biology".
Press release by "idw - Informationsdienst Wissenschaft" from 21 June 2024
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