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New cell types discovered in fatty tissue
Researchers from several countries have identified new subtypes of human fat cells for the first time. This was made possible by an innovative method of single-cell sequencing that allows thousands of cells to be analysed simultaneously. Scientists from Leipzig University Medicine were also involved in the study published in Nature Genetics.
12/03/2025
The researchers analysed samples from the Leipzig Obesity BioBank, among others. The results show that fat cells differ significantly in their biological function. Classical fat cells, for example, control glucose and fat metabolism, while so-called non-classical fat cells are involved in inflammatory processes and the formation of new blood vessels. Differences between inner abdominal fat and subcutaneous fatty tissue also became apparent. The composition of the cells is strongly dependent on inflammatory reactions. The researchers want to continue their work and investigate pathological changes such as obesity or lipedema in more detail in the future. The aim is to develop personalised therapeutic approaches based on the new findings.
Press release Leipzig University Hospital from 12 March 2025The above texts, or parts thereof, were automatically translated from the original language text using a translation system (DeepL API).
Despite careful machine processing, translation errors cannot be ruled out.